Dr Lee’s Research

Dr Richard Lee has an active interest in research and surgical innovation. He has published over 50 papers including several book chapters and he has delivered over 25 presentations at local, national and international level. 

 

Dr Lee undertook a MSc in Surgical Technology at Imperial College London and a clinical research fellowship at the world renowned UCL Institute of Ophthalmology. The fellowship was funded by a National Institute for Health Research innovation grant to develop a new surgical glaucoma device leading to the award of a PhD in Ophthalmology and a prestigious international Association of Research in Vision and Ophthalmology translational research award.

Awards

 

Peer-Reviewed Publications

 

Articles

 

Abstracts

 

Book Chapters

 

Presentations

Awards

 

  • ARVO NIHR Biomedical Research Centre for Ophthalmology, International Travel Grant Award (2016)

 

  • Alcon Glaucoma Case Study Award, National Case Presentation Finalist (2013)

 

  • Kings College London, Regional Teaching Oral Case Presentation Prize (2012)

 

  • Imperial College London, Distinction Award for MSc Dissertation (2012)

 

  • NHS Innovations South East, Regional Innovation Development Prize (2012)

 

  • British Ophthalmic Anaesthesia Society (BOAS), Norwich, National Oral Presentation Prize (2011)

 

  • BOAS, Manchester, National Poster Prize (2009)

 

  • BOAS, York, National Poster Prize (2007)

Peer reviewed Publications

 

  • Bouremel Y, Lee RMH, Eames I, Brocchini S, Khaw PT. Novel approaches to model effects of subconjunctival blebs on flow pressure to improve clinical grading systems after glaucoma drainage surgery. PLoS One. 2019;14(10):e0221715.

 

  • Lee RMH, Bouremel Y, Eames I, Brocchini S, Khaw PT. Translating Minimally Invasive Glaucoma Surgery Devices. Clin Transl Sci. 2020;13(1):14–25.

 

  • Lee RMH, Bouremel Y, Eames I, Brocchini S, Khaw PT. The Implications of an Ab Interno Versus Ab Externo Surgical Approach on Outflow Resistance of a Subconjunctival Drainage Device for Intraocular Pressure Control. Transl Vis Sci Technol. 2019;8(3):58.

 

  • Henein C, Lee RMH, Khaw PT. New therapeutic avenues in glaucoma surgery. Expert Review of Ophthalmology. DOI: 10.1080/17469899.2018.1513327

 

  • Yu-Wai-Man C, Tagalakis AD, Meng J, Bouremel Y, Lee RMH, Virasami A, Hart SL, Khaw PT. Genotype-Phenotype Associations of IL6 and PRG4 With Conjunctival Fibrosis After Glaucoma Surgery. JAMA Ophthalmol. 2017 Sep 21. doi:10.1001/jamaophthalmol.2017.3407

 

  • Yu-Wai-Man C, Spender-Dene B, Lee RM, Hutchins K, Lisabeth EM, Treisman R, Bailly M, Larsen SM, Neubig R, Khaw PT. Local delivery of a novel MRTF/SRF inhibitor, CCG-222740, prevents scar tissue formation in a preclinical model of conjunctival fibrosis. Sci Rep. 2017 Mar 31; 7(1): 518

 

  • Bouremel Y, Madaan S, Lee RMH, Eames I, Wojcik A, Khaw PT. Pursing of planar elastic pockets. J Fluid Structs. 2017; 70: 261-275

 

  • Lee RMH, Thompson JR, Eke T. Severe adverse events associated with local anaesthesia in cataract surgery: 1 year national survey of practice and complications in the UK. Br J Ophthalmol. 2016; 100: 772-6

 

  • Lee RMH, Samsudin A, Bouremel Y, Brocchini S, Khaw PT. Dimensional and Flow Properties of the EX-PRESS Glaucoma Drainage Device. Invest Ophthalmol Vis Sci. 2015; 56: 8026

 

  • Lam FC, Chia SN,Lee RMH. Macular grid laser photocoagulation for branch retinal vein occlusion. Cochrane Database Syst Rev. 2015; (5): CD008732

 

  • Hyer JN,Lee RMH, Chowdhury HR, Smith HB, Dhital A, Khandwala M. National survey of back & neck pain amongst consultant ophthalmologists in the United Kingdom. Int Ophthalmol. 2015; 35: 769-75

 

  • Lee RMH, Ong GL, Lam FC, White J, Crook D, Liu CS, Hull CC. Optical functional performance of the osteo-odonto-keratoprosthesis. Cornea. 2014; 33: 1038-45

 

  • Koay SY,Lee RMH, Hugkulstone C, Rodrigues IA. A rapidly growing lid lump. BMJ Case Rep. 2014 Aug 14;2014. pii: bcr2013202979. doi: 10.1136/bcr-2013-202979

 

  • Lee RMH, Oleszczuk J, Hyer JN, Gazzard G. Patient acceptance of smartphone technology to monitor and improve glaucoma healthcare outcomes. Eye 2014; 28: 496

 

  • Hyer J, Chowdhury HR, Lee RMH, Hasan ST. Vertical gaze palsy in Parkinsonism: An alternative diagnosis to progressive supranuclear palsy. Int J Case Rep Images 2014; 5: 492–495

 

  • Lee RMH, Robson AG, Hughes EH. Electro-oculogram (EOG) findings in a case of Acute Exudative Polymorphous Vitelliform Maculopathy (AEPVM) detected following trauma. Doc Ophthalmol 2013; 127: 255-9

 

  • Lee RMH, Bunting H. Appointment duration in the eye clinic: the same across different subspecialties? Eye 2013; 27: 1224-5

 

  • Greuner AM, Lee RMH, Kourtis N, Herbert L. To the Editor: ‘Surgical Repair of Macular Fold after Vitrectomy for Bullous Rhegmatogenous Retinal Detachment’. Retina. 2013; 33: 894-7

 

  • Lee RMH, Chowdhury HR, Hyer J, Smith HB, Jones CA. Patient-Reported Benefit from Botulinum Toxin (BTX) treatment for Essential Blepharospasm: comparing two assessment scales. Ophthal Plast Reconstr Surg. 2013; 29: 196-7

 

  • Lee RMH, Dubois DJ-P, Mavrikakis I, Okera S, Ainsworth G, Vickers S, Liu CS. Opaque Intraocular Lenses: Authors’ Reply. Clin Ophthalmol. 2013; 7: 492-3

 

  • Lee RMH, Foot B, Eke T. A review of posterior capsule rupture rate between akinetic and kinetic block anaesthetic techniques. J Cataract Refract Surg 2013; 39: 128-31

 

  • Lee RMH, Lam FC, Liu CSC. “Blue-blocking intraocular implants should be used routinely during phacoemulsification surgery” – No. Eye 2012; 26: 1400-1

 

  • Smith HB, Lee RMH, Hawkes ED. Use of Mini-Monoka Stents for Punctal/Canalicular Stenosis. Br J Ophthalmol 2012; 96: 1349

 

  • Lee RMH, Lam FC, Georgiou T, Paul B, Then KY, Mavrikakis I, Avadhanam VS, Liu CS. Suturing techniques and Post-operative Management in Penetrating Keratoplasty in the United Kingdom. Clin Ophthalmol 2012; 6: 1335-1340

 

  • Lee RMH, Llewellyn M, Houston A, Hughes EH. Reversible Mental Status Change and Renal Dysfunction associated with the use of High Dose Oral Valaciclovir Therapy for Acute Retinal Necrosis. Retinal Cases & Brief Reports 2012; 6: 266–268

 

  • Lam FC, Lee RMH, Liu CSC. “Bilateral same-day cataract surgery should routinely be offered to patients” – Yes. Eye 2012; 26: 1031-2

 

  • Lee RMH, Dubois DJ-P, Mavrikakis I, Okera S, Ainsworth G, Vickers S, Liu CS. Diplopia intraocular lens implantation: a case series and lessons learnt. Clin Ophthalmol. 2012; 6: 545-9

 

  • Byard SD, Lee RMH, Chowdhury HR, Hyer J, Hart-George AL. Unilateral Isolated Extraocular Muscle Lymphoma. BMJ Case Reports 2012

 

  • Lee RMH, Hyer J, Chowdhury H, Teimory M. Ocular signs of Multiple Endocrine Neoplasia (MEN) Type 2B. J Clin Endocrinol Metab 2012; 97: 725-6

 

  • Byard SD, Lee RMH, Lam FC, Simpson AR, Liu CS. The ‘Black on Clear’ technique – A Piggyback Technique for a Black Occlusive device in Intractable Diplopia. J Cataract Refract Surg 2012; 38: 5-7

 

  • Lee RMH, Cuthbertson FM, Soderberg P, Liu CS. A possible strategy for implanting blue-blocking intraocular lenses. Acta Ophthalmol. 2011

 

  • Gomaa A, Lee RMH, Liu CSC. Polypseudophakia for cataract surgery: 10-year follow-up on safety and stability of two poly-methyl-methacrylate (PMMA) intraocular lenses within the capsular bag. Eye 2011; 25: 1090-3

 

  • Lee RMH, Jehle T, Eke T. ‘Face to face’ upright seated positioning for cataract surgery in patients who cannot lie flat: patient characteristics, surgical approach and outcomes. J Cataract Refract Surg 2011; 37: 805-9

 

  • Lee RMH, Al Raqqad N, Gomaa A, Steel DH, Bloom PA, Liu CS. Endoscopic cyclophotocoagulation in OOKP eyes. J Glaucoma. 2011; 20: 68-9

 

  • Lee RMH, Goodfield J, Liu CS. An algorithmic approach to enhance communication with the hearing impaired during phacoemulsification surgery. Eye 2011; 25: 120-1

 

  • Lee RMH, Norris J, Narwani V, Liu CS. The “2 + 1” anaesthesia technique for patients undergoing phacoemulsification cataract surgery. Br J Anaesth [eLetter] 29 April 2010

Articles

 

  • Lee RMH, Lockwood A, Khaw PT. Minimising scarring after glaucoma surgery. Glaucoma Now 2015, 3: 12-13

 

  • Lee RMH, Khaw PT: Progress in surgical management of glaucoma in the last ten years. View on Glaucoma 2015, 10(2): 14-19

 

  • Lee RMH, Al Raqqad N, Liu CSC. Organising a Course: Personal Perspectives. Eye News 2010, 17(4): 38-42 & Urology News 2011, 15 (2): 16-18

 

  • Lee RMH, Hughes EHH. Retinal Detachment and Surgery Patient Information Leaflet. Brighton and Sussex NHS Foundation Trust, July 2011

 

  • Liu CS, Lee RMH, Okera S, Syam PP, Cubbon M, Fisher M. Prevention of blood borne viral infections during ophthalmic surgery. RCOphth Clinical Guidelines, April 2010

 

  • Lee RMH. More than meets the migraine: management of acute angle closure glaucoma presenting as migraine aura in a young patient. Eye News (In Press)

Abstracts

 

  • Lee RMH, Alband M, Penny M, Hilton ST, Brocchini S, Khaw PT. Cell adhesion and protein adsorption studies of 3D printed photopolymers. Invest. Ophthalmol. Vis. Sci. 2016; 57(12):2923

 

  • Bouremel Y, Lee RMH, Eames I, Brocchini S, Khaw PT. A new method to assess the effect of conjunctiva tissue on Intra-Ocular Pressure immediately after drainage surgery. Invest. Ophthalmol. Vis. Sci. 2016; 57(12):6459

 

  • Yu Wai Man C, Lee RMH, Larsen S, Neubig R, Khaw PT. Novel MRTF/SRF inhibitors prevent conjunctival scarring after glaucoma filtration surgery: An ex vivo and in vivo study. Invest. Ophthalmol. Vis. Sci. 2016; 57(12):2927.

 

  • Lee RMH, Ong G, White J, Lam FC, Liu CS, Hull CC. Optical Functional Properties of the Osteo-odonto-keratoprosthesis (OOKP). Invest. Ophthalmol. Vis. Sci. 2012; 53(14):6060

 

  • Hyer JN, Smith HB, Lee RMH, Jones CA. Patient-Reported Benefit from Botulinum Toxin Treatment for Essential Blepharospasm; A Comparison of Two Assessment Scales. Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6749

 

  • Lee RMH, Ong G, Lam F, Liu CS. A study of the real life performance of OOKP optical cylinders. Acta Ophthalmologica 2012, 90: 0

 

  • Al Raqqad N, Lee RMH, Herold J, Liu CS. Glaucoma Considerations In OOKP. Acta Ophthalmologica 2010, 88: 0

 

  • Lam F, Gomaa A, Al Raqqad N, Lee RMH, Liu CS. OOKP Protocol Update. Acta Ophthalmologica 2010, 88: 0

 

  • Samuel DS, Lee RMH, Lim FL, Madani H. Time to break the pre-endoscopy “melaena-PPI reflex”? Gut 2005: 54 (Suppl VII) A78

Book Chapters

 

  • Lee RMH, Eke T. Choice of anaesthesia. Liu CSC (Ed). Expert Cataract Surgery. Springer Science (in press)

 

  • Lee RMH. Glaucoma. Liu CSC (Ed). Fundamentals in Ophthalmology 1e Chapter 7. Springer Science (In press)

 

  • Khaw PT, Clarke J, Lockwood A, Lee RMH, Yu-Wai-Man C. Anti-fibrotic agents in glaucoma surgery. Yanoff M & Duker JS (Eds). Ophthalmology 5e Chapter 10.30. Elsevier

 

  • Lee RMH, Dhingra S, Khaw PT. Antimetabolite-augmented trabeculectomy combined with cataract extraction for the treatment of cataract and glaucoma. Johnson SM (Ed). Cataract Surgery in the Glaucoma Patient Chapter 8. Springer Science (In press)

 

  • Lee RMH, Yu-Wai Man C, Khaw PT. Glaucoma filtration surgery (GFS) and the Moorfields Safer Surgery System: Indications, techniques and complications. A to Z of Glaucoma Surgery. (In press)

 

  • Yu-Wai Man C, Lee RMH, Khaw PT. Modulation of wound healing during and after glaucoma surgery. A to Z of Glaucoma Surgery. (In press)

Presentations

 

  • “A novel 3D printed eye flow resistance model for intraocular pressure after glaucoma surgery: R1, R2 and R3” ARVO, Hawaii (May 2018)

 

  • “The implications of an ab interno vs. ab externo surgical approach on intraocular pressure (IOP) control” UCL Institute of Ophthalmology Departmental Study Day, London (Jul 2017)

 

  • “The implications of an ab interno vs. ab externo surgical approach on intraocular pressure (IOP) control” ARVO, Baltimore (May 2017)

 

  • “The role of biocompatibility in the development of implantable ophthalmic devices” UCL Institute of Ophthalmology Departmental Study Day, London (Nov 2016)

 

  • “Cell adhesion and protein adsorption studies of 3D printed photopolymers” ARVO, Seattle (May 2016)

 

  • “The ’10-10-10’ goal in 10 minutes” UCL Institute of Ophthalmology Departmental Study Day, London (Jun 2015)

 

  • “A BOSU study of severe adverse events associated with local anaesthesia in cataract surgery” (Invited Speaker) RCOphth Annual Congress, Birmingham (May 2014) & British Ophthalmic Anaesthesia Society, Birmingham (Nov 2013)

 

  • “Interim report of severe adverse events associated with local anaesthesia in cataract surgery” British Ophthalmic Anaesthesia Society, Exeter (Nov 2012)

 

  • “Optical Functional Properties of the OOKP” EVER, Nice (Oct 2012)

 

  • “National Survey of back pain amongst UK ophthalmologists” British Oculoplastic Surgery Society, Leicester (June 2012)

 

  • “Optical Functional Properties of the OOKP” ARVO, Fort Lauderdale (May 2012)

 

  • “Patient-Reported Benefit from Botox Treatment for Essential Blepharospasm” RCOphth College Congress, Liverpool (May 2012)

 

  • “A review of posterior capsule rupture rate between akinetic and kinetic block anaesthetic techniques.” British Ophthalmic Anaesthesia Society, Norwich (Jun 2011)

 

  • “‘Black-On-Clear’ Polypseudophakia Cataract Surgery: A Novel Approach to Surgery for Patients with Complex Neurological Symptoms” RCOphth Congress, Birmingham (May 2011)

 

  • “A Histological Comparison Of Extruded And Non-extruded OOKP Lamina” Asia ARVO, Singapore (Jan 2011)

 

  • “Diplopia intraocular lens implantation: a case series and lessons learnt” UKISCRS, Brighton (Nov 2010)

 

  • “The “2+1” anaesthesia technique for patients undergoing phacoemulsification cataract surgery” British Ophthalmic Anaesthesia Society, London (Nov 2010)

 

  • “Glaucoma considerations in OOKP” EVER, Crete (Oct 2010)

 

  • “Patient satisfaction with “no speculum, no scissors” technique for sub-Tenon’s anaesthesia”, “Repositioning breaks for patients during cataract surgery: An observational study” British Ophthalmic Anaesthesia Society, Manchester (Jun 2009)

 

  • “Oculoplastic surgery performed using local anaesthesia buffered with sodium bicarbonate: Patient satisfaction survey” British Oculoplastic Surgery Society, Cambridge (Jun 2009)

 

  • “‘Face to face’ seated positioning for cataract surgery in patients who cannot lie flat: patient characteristics, surgical approach and outcomes” RCOphth Congress 2009, Manchester (May 2009)

 

  • “‘Face to face’ seated positioning for cataract surgery in patients who cannot lie flat: patient characteristics, surgical approach and outcomes” UKISCRS Annual Meeting 2008, Brighton (Nov 2008)

 

  • “Prospective audit of patient satisfaction with Bleb Needling under topical anaesthesia at the slit lamp” RCOphth Congress 2008, Liverpool (May 2008)

 

  • “Does anaesthesia technique have an effect on the outcome of glaucoma surgery? A world-wide survey of opinion leaders in glaucoma” World Congress of Ophthalmic Anaesthesia, Cairo (Feb 2008)

 

  • “Prospective audit of patient satisfaction with Bleb Needling & Yag Iridotomy under topical anaesthesia at the slit lamp” British Ophthalmic Anaesthesia Society, York (Jun 2007)